Signs and Symptoms of ALS – Part Two

The cause and pathophysiology of Amyotrophic lateral sclerosis seems, upon further medical health care research to be a consistent neurodegenerative disorder. The motor neurons that run throughout the body begin to fail and die causing a cascading failure of motor coordination of any type.
The medical health care physicians researching this deadly disease have come to a consensus that it is a genetic mutation of some sort that manifests in the muscles. This is a gene that is coded as a critical enzyme involved in the protection of mitochondria whose main function is to guard against oxidative stress.
The health insurance industry who has long-term clients suffering from Amyotrophic lateral sclerosis (ALS) understand well how this degenerative disease eats away at the individual until it has consumed the entire body. This is also another one of the very expensive long-term chronic disorders that cost the health insurance companies millions of dollars annually.
Regardless if the individual has, an affordable health insurance policy or universal health care the cost is still very expensive as is the list of medical health care prescription drugs the individual must consume regularly. What the health insurance industry and the medical health care physicians find interesting is the common denominator to the aging process in general.
Even during the long slow aging process, the progressive damage to mitochondrial DNA is the progressive failure, which the mitochondria are usually protected from oxidative stress. This is a point of interest to the various health insurance providers because of the link to the common aging process. The failure in the management of oxidative stress within the mitochondria has an undesirable cascading effect.
1. Acceleration of apoptosis or programmed cell death
2. Health care damage to other cellular organelles
3. Disorders of protein folding
4. Oxidative stress within the mitochondria
The one common denominator is the simple fact that Amyotrophic lateral sclerosis (ALS) does not appear in the same chain of events with each individual. One individual may experience health care concerns because of weakness in the legs and the loss of balance. Another individual may experience health care concerns with the temporary loss of their arms leaving behind a tingling sensation.
This is one of the most common causes for the primary medical health care physician to misdiagnosis the disease upon the initial examination. When a medical health care physician thinks that Amyotrophic lateral sclerosis (ALS) is a strong possibility, an IMG or electromyography is requested for final determination.